This review highlights rosin's properties and applications in drug delivery and biomedical fields, suggesting its therapeutic potential.
Introduction: Rosin is a gum resin primarily composed of diterpenoids, which are de-rivatives of abietane- and pimarane-type acids. This natural polymer exhibits a unique physico-chemical profile, making it suitable for various pharmaceutical drug delivery systems. The polymer can cross-link either through a catalytic process in an acidic medium or via free radical polymeri-zation under UV radiation. Methods: This review thoroughly examined review articles and research papers from reputable journals concerning rosin. Extensive readings and discussions were conducted to summarize re-searchers' findings regarding the properties of the rosin polymer. Results: Rosin has been widely studied for its applications in various cosmetic products, drug de-livery systems, and environmental cleaning agents. Additionally, the polymer exhibits multiple bi-omedical activities, including anti-inflammatory, antifungal, antiulcer, antimicrobial, and antitumor effects. Several studies have reported satisfactory results supporting its pharmaceutical and bio-medical applications. Discussion: Rosin’s versatile cross-linking ability, biocompatibility, and inherent therapeutic ac-tivity make it a valuable polymer for pharmaceutical and biomedical applications. Its therapeutic potential and formulation flexibility support its use in diverse drug delivery systems. Conclusion: This review highlights a research gap indicating the need for precise in vivo studies to clarify the polymer's molecular pharmacology, pharmacokinetics, and pharmacodynamics.
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Negi et al. (2026) studied this question.
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