Key result
TyG index links to the non-dipper hypertension phenotype, reflecting metabolic and cardio-renal stress.
Why the study?
Are inflammatory and metabolic indices, specifically the TyG index, associated with the non-dipper hypertensive phenotype?
Observational
Are inflammatory and metabolic indices, specifically the TyG index, associated with the non-dipper hypertensive phenotype?
The TyG index is a practical and cost-effective clinical tool for multidimensional cardiometabolic and cardio-renal risk assessment in non-dipper hypertension.
Supports TyG for practical cardiometabolic and cardio-renal risk assessment in non-dipper hypertension; extends evidence but remains hypothesis-generating.
The TyG index serves as a significant independently associated with the non-dipper hypertension phenotype, reflecting predominant metabolic and cardio-renal stress rather than cellular inflammation. These findings suggest that clinical management should extend beyond blood pressure control to include early optimization of insulin resistance and atherogenic lipid imbalance. Ultimately, the TyG offers a practical and cost-effective clinical tool for multidimensional cardiometabolic and cardio-renal risk assessment.
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Kandemir et al. (2026) conducted an observational in Hypertension (dipper and non-dipper phenotypes). TyG index was evaluated on Association with non-dipper hypertension phenotype. The TyG index is significantly and independently associated with the non-dipper hypertension phenotype, reflecting predominant metabolic and cardio-renal stress.
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