Key result
A high TyG index (>8.7) was independently associated with impaired left ventricular diastolic function and structural abnormalities, including increased LAVi and E/e' ratio (p<0.001).
Why the study?
Factors other than high BP may drive LV diastolic dysfunction and structural abnormalities in hypertension, motivating evaluation of the relationship between TyG index and these cardiac changes.
Does a high triglyceride glucose index correlate with unfavorable changes in left ventricular diastolic function and structure in newly diagnosed hypertensive patients?
Cross-Sectional (n=119)
Does a high triglyceride glucose index correlate with unfavorable changes in left ventricular diastolic function and structure in newly diagnosed hypertensive patients?
p-value: p=<0.001
A high triglyceride glucose index is independently associated with impaired left ventricular diastolic function and structural abnormalities in newly diagnosed, untreated hypertensive patients without diabetes.
No takes yet. Share an insight, caveat, or question.
May flag metabolic risk for diastolic impairment; hypothesis-generating and should not yet change practice.
Şanlıalp et al. (2021) conducted a cross-sectional in Hypertension (n=119). High triglyceride glucose (TyG) index (>8.7) vs. Low TyG index (<8.7) was evaluated on Left ventricular diastolic function and structure (LAVi, LVMI, E/e' ratio, e' velocity, E/A ratio) (p=<0.001). A high TyG index (>8.7) was independently associated with impaired left ventricular diastolic function and structural abnormalities, including increased LAVi and E/e' ratio (p<0.001).
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