October 19, 2022Circulation236 citationsOpen Access
View Full PaperCoronary Arterial Spasm During Pulsed Field Ablation to Treat Atrial Fibrillation
Structured PICO
Does pulsed field ablation adjacent to coronary arteries provoke coronary vasospasm in patients treated for atrial fibrillation?
P
Population
Patients undergoing pulsed field ablation to treat atrial fibrillation
I
Intervention
Pulsed field ablation delivered adjacent to a coronary artery
C
Comparator
Pulsed field ablation at locations remote from coronary arteries
O
Outcome
Coronary vasospasmsafety
Pulsed field ablation near coronary arteries can cause subclinical vasospasm, highlighting the need for awareness and potential prophylactic use of nitroglycerin.
Abstract
Coronary vasospasm was not provoked during PFA at locations remote from coronary arteries, but when the energy is delivered adjacent to a coronary artery, PFA routinely provokes subclinical vasospasm. This phenomenon is attenuated by nitroglycerin, administered either post hoc to treat spasm or as prophylaxis.