Does goal-directed haemodynamic and fluid therapy improve peri-operative outcomes?
Although peri-operative goal-directed therapy is associated with reduced morbidity and mortality, the low quality and high heterogeneity of current evidence highlight the need for adequately powered trials.
Peri-operative modern goal-directed therapy reduces morbidity and mortality. Importantly, the quality of evidence was low to very low (e.g. Grading of Recommendations, Assessment, Development and Evaluation scoring), and there was much clinical heterogeneity among the goal-directed therapy devices and protocols. Additional well designed and adequately powered trials on peri-operative goal-directed therapy are necessary.
Chong et al. (Wed,) studied this question.