Why the study?
Does arginase inhibition reduce endothelial dysfunction and blood pressure rising in spontaneously hypertensive rats?
Does arginase inhibition reduce endothelial dysfunction and blood pressure rising in spontaneously hypertensive rats?
Arginase inhibition may represent a potential therapeutic target for mitigating endothelial dysfunction and hypertension based on preclinical models.
Our results showed that arginase inhibition reduced endothelial dysfunction and blood pressure rising in SHR.
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Demougeot et al. (2005) studied this question.
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