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Systematic review reveals uncertain diagnostic differences between needle biopsy techniques in lung lesion patients, suggesting core-needle biopsy improves specificity for benign lesions.
The evidence is currently insufficient to support a difference between fnab and cnb in identifying lung malignancies in patients with lung lesions. Compared with fnab, cnb might have a higher specificity to diagnose specific benign lesions. Well-designed, good-quality studies comparing fnab with cnb for diagnostic characteristics and yields in diagnosing lung cancer should be encouraged.
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Yao et al. (2012) studied this question.
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