Does acute ischaemic preconditioning protect against skeletal muscle infarction in pigs?
Ischaemic preconditioning protects pig skeletal muscle against infarction and is associated with lower energy metabolism, though it requires a higher threshold than cardiac muscle.
The protective effect of preconditioning can be induced in pig skeletal muscle but at a higher threshold than reported previously in pig cardiac muscle (one cycle). Preconditioning of pig skeletal muscle is associated with a lower energy metabolism during sustained ischaemia. At the present time, it is not known if this energy sparing effect is a major mechanism of ischaemic preconditioning against infarction in skeletal muscles.
Pang et al. (Thu,) studied this question.