Why the study?
To review conceptual insights, technical breakthroughs, and clinical trials in cardioimmunology to provide historical context for a compendium on cardioimmunology, myocardial function, and disease.
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Design
Review
This review highlights the historical context and emerging insights in cardioimmunology, emphasizing its role in understanding the immunologic basis of various cardiovascular diseases.
Over the past 30 years, the field of cardioimmunology has moved from being dismissed as a field that was chasing an epiphenomenon of little biological consequence to a scientific discipline that is providing important new insights into the immunologic basis for hypertension, atherosclerosis, myocarditis, pericarditis, autoimmune heart disease, and heart failure. In this article, we will review the conceptual insights and technical breakthroughs that have allowed the field to move forward, as well as the clinical trials in the cardioimmunology space, to provide a historical context for the articles that will appear in the compendium that is focused on the interface between cardioimmunology, myocardial function, and disease.
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Douglas L. Mann (2024) studied this question.
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