Why the study?
Does a calcium channel blocker and diuretic prescribing cascade increase the rate of severe adverse events in a population-based cohort?
Does a calcium channel blocker and diuretic prescribing cascade increase the rate of severe adverse events in a population-based cohort?
The CCB-diuretic prescribing cascade is associated with an increased rate of severe adverse events, highlighting the need for medication review and optimization.
Draft 1: Highlights the critical need for medication review when adding diuretics to CC.
The CCB-diuretic prescribing cascade was associated with an increased rate of SAEs, suggesting harm beyond prescribing a second drug therapy. Our study raises awareness of the downstream impact of the CCB-diuretic prescribing cascade at a population level and provides an opportunity for clinicians who identify this prescribing cascade to review their patients' medications to determine if they can be optimized.
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Rochon et al. (2023) studied this question.
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