Does FFR-guided PCI optimization directed by high-definition IVUS improve post-PCI FFR and reduce TVF at 1 year compared to standard of care?
While IVUS-guided post-PCI FFR optimization improves physiological outcomes (FFR), it does not translate to a significant reduction in 1-year target vessel failure, potentially due to low overall event rates.
IVUS-guided post-PCI FFR optimization significantly improved post-PCI FFR. Because of lower-than-expected event rates, post-PCI FFR optimization did not significantly lower TVF at the 1-year follow-up.
Neleman et al. (Mon,) studied this question.