Prospective cohort study reveals low recurrence and stable cognition with medication alone in adult ischemic moyamoya disease without misery perfusion, suggesting surgery may be safely deferred.
Among adult patients receiving medication alone for symptomatically ischemic MMD without cerebral misery perfusion, the incidence of recurrent ischemic events was 3% per 2 yr. In patients without recurrent ischemic events, cerebral hemodynamics and cognitive function had not deteriorated by 2 yr after the last event.
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Miyoshi et al. (2018) studied this question.
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