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June 14, 2026European Journal of NeurologyOpen Access

Clinical Efficacy of Revascularization Surgery for Moyamoya Angiopathy: Long‐Term Results of a European Cohort

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Authors

RMRobert MertensCharité - Universitätsmedizin BerlinIEIbrahim EfeDüsseldorf University HospitalFMFriedrich MroskHumboldt-Universität zu Berlin

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Overview

Randomized clinical trial demonstrates favorable outcomes in European Moyamoya angiopathy patients post-surgery, suggesting surgical benefits.

Key Points

  • This study aims to evaluate the long-term outcomes of European patients with moyamoya angiopathy following surgical revascularization.
  • Included 276 moyamoya angiopathy patients treated surgically between 1998 to 2023.
  • Conducted retrospective data analyses and logistic regressions to find predictors of unfavorable outcomes.
  • Follow-up comprised clinical evaluations and electronic questionnaires.
  • Complications occurred in 6.3% of surgeries, with a perioperative stroke risk of 2.6%.
  • 86.3% of patients had mRS scores of 0–2, and a bypass patency rate of 95.7% was achieved.
  • Preoperative stroke and silent ischemic MRI lesions were significant predictors of unfavorable outcomes.

Cite This Study

Mertens et al. (2026) studied this question.

synapsesocial.com/papers/6a2e465cb1cc60ccdea8b275https://doi.org/10.1111/ene.70664
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Combined Direct and Indirect Revascularization for Adults with Moyamoya Disease: A Single-Center Retrospective Study2024
  2. 2Cognitive and Functional Outcomes in Adults with Moyamoya Post-Revascularization2025
  3. 3Longitudinal neurocognitive outcomes and predictors after unilateral combined cerebral revascularization in adult moyamoya vasculopathy2025 · 1 citations
  4. 4Outcomes of bypass surgery in asymptomatic moyamoya angiopathy: A multicenter study with propensity-score weighting2026
  5. 5Surgical revascularization versus nonsurgical management in children with symptomatic moyamoya arteriopathy: a North American multicenter cohort study2026