Why the study?
Myocardial replacement fibrosis is a major feature of hypertrophic cardiomyopathy, but its characteristics have not been well delineated.
Does the extent of late gadolinium enhancement on cardiac MRI predict all-cause death in patients with hypertrophic cardiomyopathy?
Does the extent of late gadolinium enhancement on cardiac MRI predict all-cause death in patients with hypertrophic cardiomyopathy?
In patients with hypertrophic cardiomyopathy, a greater extent of myocardial replacement fibrosis on cardiac MRI is associated with a higher risk of all-cause death, regardless of its regional distribution.
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LGE extent may aid HCM risk stratification; hypothesis-generating for fibrosis-targeted interventions.
Liu et al. (2021) studied this question.
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