August 1, 2023JACC Heart Failure49 citationsOpen Access
Effect of Sotagliflozin on Early Mortality and Heart Failure-Related Events
Structured PICO
Does sotagliflozin started before discharge reduce cardiovascular deaths and heart failure events in patients with type 2 diabetes hospitalized for worsening heart failure?
P
Population
Patients with type 2 diabetes hospitalized for worsening heart failure (WHF)
I
Intervention
Sotagliflozin started before discharge
O
Outcome
Cardiovascular deaths and heart failure events through 30 and 90 days after dischargecomposite
Initiating sotagliflozin prior to hospital discharge in patients with type 2 diabetes and worsening heart failure significantly reduces early cardiovascular mortality and heart failure events.
Abstract
Starting sotagliflozin before discharge in patients with type 2 diabetes hospitalized for WHF significantly decreased cardiovascular deaths and HF events through 30 and 90 days after discharge, emphasizing the importance of beginning sodium glucose cotransporter treatment before discharge.