Anatomical change during radiotherapy for head and neck cancer, and its effect on delivered dose to the spinal cord

David J. Noble; P. Yeap; Shannon Y.K. Seah; Karl Harrison; Leila E.A. Shelley; Marina Romanchikova; Amy Bates; Yaolin Zheng; Gillian C. Barnett; Richard Benson; Sarah Jefferies; S. Thomas; R. Jena; N.G. Burnet

doi:10.1016/j.radonc.2018.07.009

July 23, 2018Radiotherapy and OncologyOpen Access

Anatomical change during radiotherapy for head and neck cancer, and its effect on delivered dose to the spinal cord

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Key Points

To evaluate how anatomical changes and weight loss during radiotherapy for head and neck cancer affect the delivered radiation dose to the spinal cord under daily image guidance.
Assessed delivered versus planned spinal cord maximum dose (D2%) across radiation fractions in patients undergoing daily image-guided radiotherapy.
Tracked patients experiencing marked anatomical variations and weight loss throughout the treatment course.
Discrepancies between planned and delivered spinal cord D2% remain small when daily image guidance is utilized.
Patients with substantial anatomical alteration or weight loss do not exceed spinal cord safety margins, eliminating the need for adaptive replanning solely for cord protection.

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Implication

Dosimetric evaluation demonstrates minimal changes in delivered spinal cord dose during head and neck radiotherapy, indicating adaptive replanning is rarely necessary for spinal cord safety.

Abstract

Differences between delivered and planned spinal cord D2% are small in patients treated with daily IG. Even patients experiencing substantial weight loss or anatomical change during treatment do not require adaptive replanning for spinal cord safety.

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Cite This Study

Noble et al. (2018) studied this question.

synapsesocial.com/papers/69df1420d5404a0bea591d75 https://doi.org/10.1016/j.radonc.2018.07.009

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Anatomical change during radiotherapy for head and neck cancer, and its effect on delivered dose to the spinal cord

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Anatomical change during radiotherapy for head and neck cancer, and its effect on delivered dose to the spinal cord

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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