ZBP1 Protects Against mtDNA-Induced Myocardial Inflammation in Failing Hearts

Nobuyuki Enzan; Shouji Matsushima; Soichiro Ikeda; Kosuke Okabe; Akihito Ishikita; Taishi Yamamoto; Masashi Sada; Ryo Miyake; Yoshitomo Tsutsui; Ryohei Nishimura; Takayuki Toyohara; Yuki Ikeda; Yoko Shojima; Hiroko Deguchi Miyamoto; Tomonori Tadokoro; Masataka Ikeda; Kohtaro Abe; Tomomi Ide; Shintaro Kinugawa; Hiroyuki Tsutsui

doi:10.1161/circresaha.122.322227

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Abstract

Our study reveals unexpected protective roles of ZBP1 against cardiac remodeling as an endogenous suppressor of mtDNA-induced myocardial inflammation.

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Enzan et al. (2023) studied this question.

synapsesocial.com/papers/69df142ad9e0feb21c591717 https://doi.org/10.1161/circresaha.122.322227

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ZBP1 Protects Against mtDNA-Induced Myocardial Inflammation in Failing Hearts

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Abstract

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ZBP1 Protects Against mtDNA-Induced Myocardial Inflammation in Failing Hearts

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