Despite the association between chronic heart failure and inflammatory cytokines, trials targeting inflammation have largely been negative, indicating a need for further research into the immune system's role in disease progression.
No takes yet. Share an insight, caveat, or question.
Negative trials despite cytokine associations warrant clinical caution against broad anti-inflammatory strategies in chronic HF; leaves open refined immunomodulatory targets.
Dick et al. (2016) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: