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July 9, 2019Journal of Gastrointestinal OncologyOpen Access

Frequency and prognostic significance of isocitrate dehydrogenase 1 mutations in cholangiocarcinoma: a systematic literature review

Audra Boscoe Catherine Rolland Robin Kate Kelley

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Abstract

This systematic review substantiates the prevalence of mIDH1 in CC and further characterizes clinical, pathologic, and genetic covariates within this sub-population. Co-mutation data may inform future studies of mechanisms of response and resistance to mIDH1-targeted therapies.

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Boscoe et al. (2019) studied this question.

synapsesocial.com/papers/69df24013b0ba53fb37a189a https://doi.org/10.21037/jgo.2019.03.10

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