What question did this study set out to answer?

The research aims to clarify the concept of cytokine storm syndromes and their underlying mechanisms.

April 15, 2026Open Access

Re-evaluating cytokine storm syndromes: dysregulated host defense or contextual immune adaptation?

Key Points

The research aims to clarify the concept of cytokine storm syndromes and their underlying mechanisms.
Reviewed existing literature on cytokine storm syndromes.
Analyzed cases across infectious, inflammatory, and iatrogenic contexts.
Critically evaluated definitions and mechanistic explanations of cytokine storms.
Cytokine storm syndromes demonstrate varied definitions across different diseases.
Mechanistic imprecision complicates understanding of host defense responses.
Contextual immune adaptation plays a significant role in immunopathology.

Abstract

Cytokine storm syndromes have become a much-invoked concept to describe severe immunopathology in infectious, inflammatory, and iatrogenic diseases, but the concept is poorly defined and often mechanistically imprecise. High ... | Find, read and cite all the research you need on Tech Science Press

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Authors

Abhishek Vijukumar

Indo Soviet Friendship College of Pharmacy

Hardik Kumar

Dr. Hari Singh Gour University

Shilpa Debnath

Indo Soviet Friendship College of Pharmacy

Journals

European Cytokine Network

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Re-evaluating cytokine storm syndromes: dysregulated host defense or contextual immune adaptation?

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

References and Citations

Citation Network

Connected Papers

Discussion

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