Key result
Left bundle branch-optimized cardiac resynchronization therapy (LOT-CRT) in a 78-year-old woman with pacing-induced cardiomyopathy triggered early post-procedural ventricular fibrillation.
Case Report (n=1)
This case highlights the potential for early post-procedural ventricular arrhythmias following LOT-CRT in structurally compromised ventricles, underscoring the need for vigilant monitoring.
Warrants vigilant early monitoring after LOT-CRT in compromised ventricles; hypothesis-generating for post-procedural arrhythmia risk.
Left bundle branch-optimized cardiac resynchronization therapy (LOT-CRT), combining left bundle branch area pacing (LBBAP) with a left ventricular lead, offers physiological activation and improved synchrony compared with conventional biventricular pacing. We report a 78-year-old woman with pacing-induced cardiomyopathy who underwent LOT-CRT, resulting in QRS narrowing but notable QT prolongation and T-wave inversions. On the first post-implant day, she developed ventricular fibrillation triggered by premature ventricular complexes, without reversible metabolic or ischemic cause. This case highlights the potential for early post-procedural ventricular arrhythmias in structurally compromised ventricles, underscoring the importance of vigilant monitoring and individualized risk assessment following LOT-CRT.
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Kesriklioğlu et al. (2026) conducted a case report in Pacing-induced cardiomyopathy (n=1). Left bundle branch-optimized cardiac resynchronization therapy (LOT-CRT) was evaluated on Ventricular fibrillation. Left bundle branch-optimized cardiac resynchronization therapy (LOT-CRT) in a 78-year-old woman with pacing-induced cardiomyopathy triggered early post-procedural ventricular fibrillation.
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