Why the study?
Is there a difference in markers of adipose tissue inflammation between overweight women with polycystic ovary syndrome and weight-matched controls?
Is there a difference in markers of adipose tissue inflammation between overweight women with polycystic ovary syndrome and weight-matched controls?
Adipose tissue inflammation in PCOS is primarily driven by being overweight rather than the PCOS diagnosis itself.
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Overweight drives adipose inflammation in PCOS; leaves open independent effects in lean phenotypes.
Overweight, rather than the PCOS diagnosis per se, appears to be the main explanatory variable for elevated adipose tissue inflammation in patients with PCOS.
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Lindholm et al. (2011) studied this question.
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