What is the profile and what are the determinants of cognitive impairment in patients with chronic heart failure?
Cognitive impairment is a common comorbidity in chronic heart failure, driven by disease severity and genetic factors like ApoE genotype.
Cognitive dysfunction is relatively common in patients with CHF, with deficits being most prominent in the domains of executive function, memory, language, and mental speed. Disease severity and ApoE genotype are likely to be important determinants for cognitive impairment in patients with chronic CHF.
Vogels et al. (Sat,) studied this question.