Why the study?
Does Transcatheter Tricuspid Valve Replacement (TTVR) improve symptoms and end-organ function in patients with tricuspid regurgitation in a real-world setting?
Does Transcatheter Tricuspid Valve Replacement (TTVR) improve symptoms and end-organ function in patients with tricuspid regurgitation in a real-world setting?
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Real-world TTVR effectively improves symptoms and end-organ function, especially in severe TR, though baseline RV dysfunction predicts adverse outcomes and conduction disturbances increase pacemaker risk.
TR elimination following TTVR in a real-world setting was associated with significant symptom and end-organ functional improvement. Patients with massive or torrential TR were more likely to experience functional improvement. Pre-existing conduction disturbances are associated with increased risk for pacemaker implantation, while baseline right ventricular dysfunction is a strong predictor of adverse clinical outcomes.
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Angellotti et al. (2025) studied this question.
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