Why the study?
Oxidative stress contributes to heart failure progression, leading the authors to analyze whether activities of superoxide dismutase and its isoenzymes serve as prognostic factors in dilated cardiomyopathy.
Does serum superoxide dismutase (SOD) activity predict adverse outcomes in patients with nonischemic dilated cardiomyopathy?
Population
109 patients with nonischemic dilated cardiomyopathy
Comparison
Serum activities of total SOD, MnSOD, and CuZnSOD
Follow-up
5-year
Authors
Loading...
May support SOD activity for risk stratification in nonischemic dilated cardiomyopathy; hypothesis-generating, needs prospective validation.
Does serum superoxide dismutase (SOD) activity predict adverse outcomes in patients with nonischemic dilated cardiomyopathy?
Increased activities of total serum SOD and its isoenzymes correspond with a poor prognosis and may serve as useful predictors of adverse outcomes in patients with nonischemic dilated cardiomyopathy.
Romuk et al. (2019) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: