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This research investigates how hydrostatic pressure affects the formation and stability of epithelial domes in tissues.

April 16, 2026Soft Matter0 citations

Effects of hydrostatic pressure on epithelial dome formation and stability

JMJianfeng MengHong Kong Polytechnic University GXGuangsong XieSecond Affiliated Hospital of Zhejiang University YZYifei ZhengUniversity of Southern California

Key Points

This research investigates how hydrostatic pressure affects the formation and stability of epithelial domes in tissues.
Analyzed the collective cell behavior under varying hydrostatic pressure conditions
Examined tissue samples for structural integrity and stability over time
Utilized imaging techniques to visualize epithelial dome formation
Hydrostatic pressure enhances the stability of epithelial domes
Increased pressure correlates with improved structural integrity of hollow tissues
Collective cell responses were significantly altered under different pressure levels

Abstract

Hydrostatic pressure in living organisms is crucial to the formation and stability of hollow structures in tissues and organs. However, the underlying mechanisms governing the collective cell responses to the...

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