Recurrences and Survival in Oropharyngeal Squamous Cell Carcinoma According to p16 Status and Extranodal Extension

Key Points

This research examines how p16 status and extranodal extension affect prognosis in oropharyngeal squamous cell carcinoma (OPSCC).
Analyzed the relationship between p16 status and prognosis in OPSCC.
Evaluated the effect of extranodal extension on survival outcomes based on HPV status.
HPV status alters the prognostic implications of extranodal extension in OPSCC.
Findings suggest distinct survival patterns depending on p16 and HPV status.

P16 status influences recurrence and survival in oropharyngeal squamous cell carcinoma, indicating the need for tailored prognostic assessments.

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Boscolo-Rizzo et al. (2026) studied this question.

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