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January 1, 2026Clinical Laboratory

Analysis of Blood Group Antigens as Risk Factors for Thrombosis in Polycythemia Vera Patients

Jay Han Hyung Cho Mi Hwang Taewon Kang Howon Lee Kwangsang Koh Sung-Eun Lee Hee-Je Kim Dong Jekarl Myungshin Kim Yonggoo Kim

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Key Points

The study aims to evaluate the relationship between blood group antigen expression and thrombosis risk in polycythemia vera (PV) patients.
Analyzed levels of Indian (CD44) expression in red blood cells (RBCs) of PV patients.
Correlated CD44 levels with occurrences of thrombotic events.
Conducted a risk assessment for thrombosis based on biomarker levels.
Higher CD44 MFI levels in RBCs were linked to increased thrombotic events.
CD44 expression may serve as a biomarker for predicting thrombotic risk in PV patients.

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Implication

Analysis reveals that RBC CD44 expression correlates with thrombotic risk in polycythemia vera, suggesting biomarker potential.

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Cite This Study

Han et al. (2026) studied this question.

synapsesocial.com/papers/69e07e582f7e8953b7cbf556 https://doi.org/10.7754/clin.lab.2025.250638

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