Does benign aortic valve thickening progress to significant aortic stenosis and increase morbidity and mortality?
Aortic valve thickening without stenosis may progress to significant aortic stenosis, potentially explaining increased morbidity and mortality in these patients.
Aortic valve thickening without stenosis is common, and it may progress to significant AS. It is possible that this development of AS may be responsible for some of the increased morbidity and mortality in patients with AVT.
Cosmi et al. (2002) studied this question.