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Digital image processing quantifies stromal riboflavin in ex vivo models, suggesting real-time monitoring could improve treatment accuracy.
The proposed digital slit-lamp analysis provides a simple, objective, and reproducible method for quantifying stromal riboflavin fluorescence. The strong correlation between FS and spectrophotometric measurements supports its use as a noninvasive surrogate for stromal riboflavin assessment. With further in vivo validation, this approach may enable real-time monitoring and optimization of transepithelial CXL protocols.
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Coşkun et al. (2026) studied this question.
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