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April 18, 2026Russian Journal of Archive of Pathology

Prognostic role of histologic features in low-grade serous ovarian carcinoma: association of invasion and desmoplasia patterns with tumor recurrence

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Authors

ABA.S. BadlaevaAAA.V. AsaturovaATA.V. Tregubova

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Overview

Study reveals histologic features affecting tumor recurrence in low-grade serous carcinoma, suggesting important prognostic implications.

Key Points

  • To explore the relationship between invasion patterns, stromal desmoplasia, and relapse-free survival in low-grade serous carcinoma.
  • Reviewed 26 ovarian low-grade serous carcinoma samples from patients aged 30 to 83 years.
  • Identified macropapillary and micropapillary invasion patterns and stromal desmoplasia through pathology review.
  • Assessed survival using the Kaplan-Meier method.
  • Overall survival was 96.1% and relapse-free survival was 76.9%.
  • Macropapillary invasion pattern was found in 73.1% of cases; micropapillary in 15.4%.
  • Tumor recurrence was 16% in macropapillary cases, 75% in micropapillary, and 100% in desmoplasia cases.

Cite This Study

Badlaeva et al. (2026) studied this question.

synapsesocial.com/papers/69e3201440886becb653f254https://doi.org/10.17116/patol20268802120
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Also Consider

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  1. 1818 Evaluation of the prognostic potential of histopathological subtyping in high-grade serous ovarian carcinoma2024
  2. 2Study on prognostic factors of low-grade serous ovarian cancer and establishment of nomogram prognostic model2024
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  4. 4Seromucinous borderline tumor-associated high-grade ovarian cancers2024
  5. 5Prognostic Value of Morphological Characteristics and Immune Microenvironment in High-Grade Serous Cancer (HGSC)2026