Efficacy of intravenous reperfusion treatment in acute ischaemic stroke with age-dependent variables: a 10-year single-centre study

This study underscores age as a key predictor of outcomes following intravenous thrombolysis in acute ischaemic stroke. Among patients aged >75 years, prolonged symptom-to-needle time, atrial fibrillation, higher baseline NIHSS and DM were significantly associated with poor clinical outcomes. Younger patients demonstrated more favourable recovery profiles, whereas advancing age was associated with higher mortality. Notably, DM consistently emerged as a risk factor for unfavourable outcomes across all age groups.