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April 18, 2026BMC Public HealthOpen Access

Urban living is linked to earlier hypertension and diabetes onset, leaving ~30% hypertension-free with age.

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Why the study?

Hypertension and diabetes frequently co-exist and contribute substantially to cardiovascular morbidity, premature mortality, and healthcare costs in ageing populations, requiring evaluation across the life course.

Population

60,643 adults aged 45 years and above in India

Design

Nationally representative cross-sectional survey analysis

Key result

The probability of remaining free from hypertension drops to less than 30% with age, whereas for diabetes it remains around 65%, with urban residents experiencing earlier onset for both conditions.

Authors

ACAditi ChakrabortySYSuryakant Yadav

Discussion

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Overview

Supports sex-sensitive risk assessment in older Indians; extends evidence on obesity, family history, and comorbidity as predictors across all ages.

Key Points

  • The research aims to examine the age-related patterns and risk factors associated with hypertension and diabetes among older Indians.
  • Utilized data from the Longitudinal Ageing Study in India (LASI, 2017-18) with a multi-stage sampling approach.
  • Analyzed 60,643 adults aged 45 and above after merging individual and biomarker datasets.
  • Employed Kaplan-Meier survival analysis and modified Poisson regression to assess age at diagnosis and prevalence.
  • Undiagnosed hypertension declines faster with age compared to diabetes, indicating earlier diagnosis.
  • Urban residents show earlier diagnosis and a sharper decline in undiagnosed cases for both conditions.
  • Hypertension prevalence increases with age, while diabetes peaks in the 65-74 age group, especially noticeable in 55-64 age group.

Study Design

Type

Cross-Sectional (n=60,643)

Multicenter

Yes

Structured PICO

P
Population
60,643 adults aged 45 years and above from the Longitudinal Ageing Study in India (LASI, 2017-18), a nationally representative survey across rural and urban areas.
O
Outcome
Age at onset of hypertension and diabetes, age-specific patterns of reported age at diagnosis, prevalence, and associated risk factors

The study highlights the need for life course-oriented, socio-demographically responsive strategies, particularly in urban populations, to prevent and manage the rising burden of hypertension and diabetes in India's ageing population.

Limitations

  • Cross-sectional design limits causal inference
  • Reliance on self-reported age at diagnosis
  • Missing data on key covariates required multiple imputation
  • Cross-sectional design limits causal inference and true longitudinal tracking

Cite This Study

Chakraborty et al. (2026) conducted a cross-sectional in Hypertension and Diabetes (n=60,643). The probability of remaining free from hypertension drops to less than 30% with age, whereas for diabetes it remains around 65%, with urban residents experiencing earlier onset for both conditions.

synapsesocial.com/papers/69e321aa40886becb6540bf0https://doi.org/10.1186/s12889-026-27284-6
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