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April 19, 2026MedicineOpen Access

Relationship between changes in BNP, PCT, and SIGIRR levels in peripheral blood and prognosis of sepsis patients caused by abdominal infection and construction of a nomogram

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Authors

SLShangzhen LiYCYunyun CuiJYJiaqi Yuan

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Overview

Investigates biomarkers predicting prognosis in sepsis patients with abdominal infection, suggesting effective clinical tools.

Key Points

  • To explore changes in serum BNP, PCT, and SIGIRR levels and their prognostic value in sepsis patients due to abdominal infection.
  • Divided 160 emergency patients based on sepsis presence into simple infection and sepsis groups.
  • Compared serum BNP, PCT, and SIGIRR levels between groups and survival conditions over 28 days.
  • Analyzed prognostic factors using binary logistic regression and constructed a nomogram based on these factors.
  • Serum levels of BNP, PCT, and SIGIRR in the sepsis group were significantly higher than in the simple infection group.
  • The death group showed significantly higher serum levels of BNP, PCT, and SIGIRR compared to the survival group.
  • The nomogram achieved a Concordance Index of 0.947, indicating excellent predictive ability.

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69e47282010ef96374d8e7f0https://doi.org/10.1097/md.0000000000048227
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