Mitochondria-Specific Protein Delivery In their Research Article (10.1002/admt.202501468), Simon Sau Yin Law, Keiji Numata, and co-workers achieve targeted and triggered release of protein cargo within intact plant mitochondria using polymer-coated carbon nanotubes. Incorporation of a mitochondrial targeting signal sequence and a protease-cleavable linker enable organelle-specific protein delivery while protecting the cargo over extended periods, with potential for broader triggered-release applications within plants.
Law et al. (Wed,) studied this question.