Why the study?
To establish normal myocardial stiffness values in healthy adults using cardiac MR elastography and assess the impact of slice location and demographic factors.
Population
125 healthy volunteers
Comparison
Myocardial stiffness across basal, mid, and apical short-axis views and demographic factors
Design
Cross-sectional study
Key result
Cardiac MR elastography in 125 healthy adults established a global myocardial stiffness of 8.1 ± 1.1 kPa and a significant apical-to-basal gradient (apex 8.7, mid 8.3, base 7.4 kPa; P<0.05).
Authors
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Age and slice location must inform cardiac MRE reference ranges; extends normative data for future diagnostic studies.
Cross-Sectional (n=125)
Cardiac MR elastography demonstrates that normal myocardial stiffness in healthy adults follows an apical-to-basal gradient and increases independently with age, providing location-specific baseline values for clinical interpretation.
Cheng et al. (2026) conducted a cross-sectional in Healthy adults (n=125). Cardiac MR elastography (MRE) was evaluated on Normal myocardial stiffness values and the impact of slice location and demographic factors. Cardiac MR elastography in 125 healthy adults established a global myocardial stiffness of 8.1 ± 1.1 kPa and a significant apical-to-basal gradient (apex 8.7, mid 8.3, base 7.4 kPa; P<0.05).