Association of Beta-Blocker Treatment with Mortality Following Myocardial Infarction in Patients with Chronic Obstructive Pulmonary Disease and Heart Failure or Left Ventricular Dysfunction: A Propensity Matched-Cohort Analysis from the High-Risk Myocardial Infarction Database Initiative

Stefano Coiro; Nicolas Girerd; Patrick Rossignol; João Pedro Ferreira; Aldo P. Maggioni; Bertram Pitt; Isabella Tritto; Giuseppe Ambrosio; Kenneth Dickstein; Faı̈ez Zannad

doi:10.1002/ejhf.647

October 24, 2016European Journal of Heart FailureOpen Access

Association of Beta-Blocker Treatment with Mortality Following Myocardial Infarction in Patients with Chronic Obstructive Pulmonary Disease and Heart Failure or Left Ventricular Dysfunction: A Propensity Matched-Cohort Analysis from the High-Risk Myocardial Infarction Database Initiative

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Key Points

To determine the association between beta-blocker treatment and mortality following myocardial infarction in patients with chronic obstructive pulmonary disease and concomitant heart failure or left ventricular dysfunction.
Conducted a propensity score-matched cohort analysis using data from the High-Risk Myocardial Infarction Database Initiative.
Evaluated high-risk myocardial infarction survivors diagnosed with chronic obstructive pulmonary disease (COPD) and heart failure or left ventricular systolic dysfunction.
Beta-blocker therapy was associated with significantly improved clinical outcomes and reduced mortality in high-risk myocardial infarction survivors with COPD.

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Implication

Propensity-matched cohort study reveals improved survival with beta-blockers in high-risk post-myocardial infarction patients with COPD, suggesting safe cardiovascular benefit.

Abstract

In the specific setting of a well-treated cohort of high-risk MI survivors, beta-blockers were associated with better outcomes in patients with COPD.

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Coiro et al. (2016) studied this question.

synapsesocial.com/papers/69e5da6ddb3f836d8f13c511 https://doi.org/10.1002/ejhf.647

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Association of Beta-Blocker Treatment with Mortality Following Myocardial Infarction in Patients with Chronic Obstructive Pulmonary Disease and Heart Failure or Left Ventricular Dysfunction: A Propensity Matched-Cohort Analysis from the High-Risk Myocardial Infarction Database Initiative

Key Points

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Implication

Abstract

Discussion

Cite This Study

Association of Beta-Blocker Treatment with Mortality Following Myocardial Infarction in Patients with Chronic Obstructive Pulmonary Disease and Heart Failure or Left Ventricular Dysfunction: A Propensity Matched-Cohort Analysis from the High-Risk Myocardial Infarction Database Initiative

Key Points

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Implication

Abstract

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