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This study aims to evaluate the prognostic influence of various clinicopathological and laboratory factors on colorectal cancer survival.

April 21, 2026Discover OncologyOpen Access

Prognostic influence of clinicopathological and laboratory factors on colorectal cancer survival in Amhara region oncology centers, retrospective cohort study, Ethiopia, 2024

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This study aims to evaluate the prognostic influence of various clinicopathological and laboratory factors on colorectal cancer survival.
Conducted a retrospective cohort study with 464 participants from July 2018 to June 2023.
Utilized Cox regression models to identify factors associated with mortality.
Included variables with a P-value < 0.25 from bivariable analysis in the multivariable Cox regression model.
Rectal cancer was associated with an adjusted hazard ratio (AHR) of 1.88 for increased mortality.
Baseline alkaline phosphatase (ALP) levels ≥ 127 IU/L correlated with an AHR of 1.56.
Late-stage cancer significantly increased mortality risk with an AHR of 3.46.

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Retrospective cohort study evaluates prognostic factors influencing colorectal cancer survival in Ethiopia, highlighting key determinants.

Walle et al. (2026) studied this question.

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Retrospective cohort study evaluates prognostic factors influencing colorectal cancer survival in Ethiopia, highlighting key determinants.