Key result
Endothelial dysfunction severity is linked to CV risk, offering a potential surrogate marker for atherosclerosis.
Why the study?
Defining new approaches for the prevention and treatment of atherosclerosis is a priority, and evaluating the current clinical utility of endothelial dysfunction as a patient care tool or surrogate marker is needed.
Design
Review
Authors
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Should not guide routine clinical practice; leaves open its role as surrogate in atherosclerosis trials.
Endothelial dysfunction serves as a marker of cardiovascular risk and may be useful as a surrogate marker for evaluating new therapeutic strategies.
Widlansky et al. (2003) conducted a review in Atherosclerosis. Endothelial function measurement was evaluated. Endothelial dysfunction severity relates to cardiovascular risk, suggesting its measurement could serve as a surrogate marker for evaluating new therapeutic strategies in atherosclerosis.
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