New three-component reaction produces CF3 S-containing vinyl sulfones, highlighting broad applications in synthetic chemistry.
A new three‐component trifluoromethylthio‐sulfonylation of allenes via copper catalysis has been established, affording a variety of CF 3 S‐containing vinyl sulfones with excellent chemo‐, regio‐, and stereoselectivity under mild conditions. This protocol exhibits wide functional group tolerance, good broad compatibility with various allenes and sulfonyl chlorides, and shows potential for applications in synthetic chemistry.
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Guo et al. (2026) studied this question.
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