What question did this study set out to answer?

This study aimed to evaluate the efficacy and safety of autologous platelet-rich plasma gel for chronic wounds unresponsive to standard care.

A Single-Institution Cohort Study of Autologous Platelet-Rich Plasma Gel for Hard-to-Heal Chronic Wounds: Potential Role in Microvascular Regeneration

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Retrospective study shows improved healing in chronic wounds, suggesting PRP benefits for microvascular issues.

This study aimed to evaluate the efficacy and safety of autologous platelet-rich plasma gel for chronic wounds unresponsive to standard care.
Included 20 patients with chronic ulcers unresponsive to 28 days of conventional therapy.
Applied PRP gel weekly for up to eight sessions.
Compared healing times using Wilcoxon signed-rank test.
All wounds achieved complete epithelialization within 12 weeks.
Healing time decreased significantly from 87.2 days during conventional therapy to 47.9 days after PRP.
No adverse events related to treatment were reported.

Fujii et al. (2026) studied this question.

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