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September 5, 2025Journal of Theoretical and Applied Vascular ResearchOpen Access

Evidence Based Efficacy of Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF) in Acute and Chronic Wound Healing: A Retrospective Case Series

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Authors

NHNina HassaniBBBernard BioulacASA. Schuh

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Overview

Retrospective analysis shows PRP and PRF improve wound healing in chronic wounds, indicating their role in regenerative therapies.

Key Points

  • Complete wound closure was achieved in 47.1% of patients receiving PRP and PRF treatments, with significant clinical improvement.
  • Pain intensity decreased by 72% based on VAS scores, indicating effective pain management during the healing process.
  • Patients were treated for various wound types, including chronic wounds like venous ulcers, enhancing the role of regenerative therapies.
  • No serious adverse events were reported, suggesting that PRP and PRF treatments are safe for patients across diverse age groups.

Cite This Study

Hassani et al. (2025) studied this question.

synapsesocial.com/papers/68bb46bd6d6d5674bccfec40https://doi.org/10.24019/jtavr.239
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparative Efficacy of Platelet‐Rich Plasma, Platelet‐Rich Fibrin, and Conventional Therapy in Chronic Non‐Healing Skin Ulcers: A Randomised Clinical Trial2026 · 1 citations
  2. 2Platelet-Rich Plasma (PRP) and Recombinant Growth Factor Therapies in Cutaneous Wound Healing: Mechanisms, Clinical Applications, and Future Directions2025
  3. 3A Single-Institution Cohort Study of Autologous Platelet-Rich Plasma Gel for Hard-to-Heal Chronic Wounds: Potential Role in Microvascular Regeneration2026
  4. 4Efficacy and Safety of Autologous Platelet-Rich Plasma Gel in the Treatment of Chronic Skin Ulcerations2024
  5. 5Platelet-rich Plasma as a Treatment Modality for Wound Healing: An Open Randomized Controlled Trial2024 · 3 citations