What question did this study set out to answer?

This research assesses the shear-dependent agreement between two viscometers used to measure whole-blood viscosity for cardiovascular risk evaluation.

April 22, 2026DiagnosticsOpen Access

Shear-Dependent Agreement and Clinical Reclassification of Whole-Blood Viscosity Measurements: A Paired Comparison of Rheovis 2000A and Hemovister

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Authors

JYJongho YiKonkuk University HJHong-Geun JungKonkuk University SLSeoung Joon LeeKonkuk University

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Implication

Paired comparison evaluates analytical agreement of devices in whole-blood viscosity measurement, suggesting implications for clinical classification.

Key Points

This research assesses the shear-dependent agreement between two viscometers used to measure whole-blood viscosity for cardiovascular risk evaluation.
Conducted a paired comparison of Rheovis 2000A and Hemovister using 300 identical blood samples.
Measured whole-blood viscosity at specified shear rates for analytical agreement analysis.
Applied linear regression and Bland–Altman analysis, evaluating clinical agreement with Cohen’s κ.
Hemovister showed consistently higher whole-blood viscosity than Rheovis 2000A across matched shear rates, particularly at lower shear rates.
The mean difference in viscosity was notably larger under clinically defined diastolic conditions compared to systolic conditions.
Categorical agreement between devices was moderate to fair, with significant reclassification observed for high-viscosity classifications.

Cite This Study

Yi et al. (2026) studied this question.

synapsesocial.com/papers/69e866ad6e0dea528ddeb0db https://doi.org/10.3390/diagnostics16081232

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Implication

Paired comparison evaluates analytical agreement of devices in whole-blood viscosity measurement, suggesting implications for clinical classification.