Key result
Narrow bifurcation angles link to ~11% cardiac death rate after TAP stenting in STEMI.
Why the study?
Does bifurcation angle impact target lesion failure in STEMI patients undergoing TAP stenting?
Cohort (n=386)
Does bifurcation angle impact target lesion failure in STEMI patients undergoing TAP stenting?
In STEMI patients undergoing TAP stenting for side branch compromise, narrow bifurcation angles (<50°) are associated with a higher risk of cardiac death and in-hospital MI compared to wider angles.
Answers are grounded in this paper and cite their sources.
Caution warranted for TAP stenting in narrow-angle STEMI bifurcations; leaves open optimal strategy pending prospective validation.
Background The T-stent and small protrusion (TAP) technique is frequently utilised as a bailout two-stent strategy during provisional bifurcation stenting. However, the impact of bifurcation angle on long-term clinical outcomes following TAP stenting in ST-elevation myocardial infarction (STEMI) remains underexploredMethods We retrospectively evaluated 386 STEMI patients who underwent TAP stenting after side branch (SB) compromise. Patients were stratified into three groups based on bifurcation angle: >70° (Group 1), 50–70° (Group 2), and <50° (Group 3). The primary endpoint was target lesion failure (TLF), defined as a composite of cardiac death, target-vessel myocardial infarction, and clinically-driven target lesion revascularization. Cox proportional hazards models were used to assess independent predictors of outcomes.Results The primary outcome (TLF) occurred in 13% of patients overall and did not differ significantly among bifurcation angle groups, although numerically higher rates were observed in the narrow angle group. In-hospital myocardial infarction (5.6%) and death (11.1%) were significantly higher in Group 3 (<50°). Cardiac death was significantly more frequent in Group 3 (11.1%; p = 0.02). Independent predictors of TLF included SB stent length, distal left main involvement, and baseline CRP, whereas larger POT balloon size was protectiveConclusion TAP stenting appears safe and effective in wide and intermediate bifurcation angles in STEMI. However, narrow angles (<50°) may portend a higher risk of adverse events, warranting cautious application and further validation through prospective studies
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Eren et al. (2026) conducted a cohort in ST-elevation myocardial infarction (STEMI) (n=386). Narrow bifurcation angle (<50°) vs. Intermediate (50-70°) and wide (>70°) bifurcation angles was evaluated on Target lesion failure (TLF), defined as a composite of cardiac death, target-vessel myocardial infarction, and clinically-driven target lesion revascularization. Narrow bifurcation angles (<50°) in STEMI patients undergoing TAP stenting were associated with significantly higher rates of cardiac death (11.1%; p=0.02) compared to wider angles.
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