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April 23, 2026Open Access

Exploring the Potential Role of Pseudomonas aeruginosa Extracellular Vesicles in Tumor Dynamics of Melanoma

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Authors

刘L刘轩竹(Xuanzhu Liu)

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Overview

Comprehensive analysis reveals Pseudomonas aeruginosa EVs enhance cell migration in melanoma, suggesting potential therapeutic avenues.

Key Points

  • The research investigates the role of Pseudomonas aeruginosa extracellular vesicles in melanoma dynamics and their interactions with tumor cells.
  • Utilized advanced spatial transcriptomics and traditional microbiome analysis to characterize tumor-associated microbes.
  • Conducted Transwell migration and wound healing assays to assess the impact of EVs on melanoma cell behavior.
  • Pseudomonas aeruginosa EVs significantly enhance A375 melanoma cell migration but do not affect cell proliferation.
  • Extracellular vesicles modulate inflammatory responses within the tumor microenvironment, influencing tumor-immune interactions.

Cite This Study

刘轩竹(Xuanzhu Liu) (2026) studied this question.

synapsesocial.com/papers/69e9b85585696592c86eba11https://doi.org/10.26036/cnp0005618
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Also Consider

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  1. 1Novel insights into extracellular vesicles: An update on biomolecules, immunomodulation and clinical strategies in skin melanoma2026 · 1 citations
  2. 2Abstract 5358: The influence of extracellular vesicles on immune cells in PDAC2024
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  4. 4Extracellular Vesicles and Their Multifaceted Roles in Cancer: Current Evidence from a Narrative Review2026
  5. 5Adipocyte-Derived Extracellular Vesicles Endow Melanoma Cells with Stem-like Traits via PGC-1α–Mediated Mitochondrial Reprogramming2026 · 3 citations