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April 23, 2026Chemical Communications0 citationsOpen Access

Mechanochemically-synthesised AIE-active receptors for selective ceftazidime sensing in high-water-content matrices

KMKrzysztof MelcerWarsaw University of TechnologyTDTim DavidHeinrich Heine University DüsseldorfBSBernd M. SchmidtHeinrich Heine University Düsseldorf

Key Points

  • Investigate a novel method for sensing ceftazidime using AIE-active receptors in water-rich environments.
  • Utilized mechanochemical synthesis to create water-insoluble, AIE-active dendritic receptors.
  • Performed selectivity tests against related β-lactams through titrations.
  • Employed DFT (Density Functional Theory) for computational analysis of interactions.
  • Achieved selective fluorescence detection of ceftazidime in up to 99 vol% water.
  • Confirmed selectivity over structurally related β-lactams via experimental titrations.
  • Demonstrated that AIE-active receptors perform effectively in high-water matrices.

Abstract

Mechanochemical synthesis of water-insoluble, AIE-active dendritic receptors enable selective fluorescence detection of ceftazidime in up to 99 vol% water. Selectivity over structurally related β-lactams was confirmed by titrations, DFT, and...

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Cite This Study

Melcer et al. (2026) studied this question.

synapsesocial.com/papers/69e9ba6b85696592c86ec90fhttps://doi.org/10.1039/d6cc01502f
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