Major depression is associated with an increased risk of developing cardiovascular disease and worse clinical outcomes, highlighting the need to address this interface in clinical practice.
Supports screening consideration in CVD; leaves open treatment effects on outcomes.
Patients with major depression are at an increased risk for developing cardiovascular disease, respond more poorly to treatment, and exhibit worse outcomes, including increased morbidity and mortality. This article reviews the relationship between depression and heart disease, with an emphasis on epidemiology, biological substrates that likely underlie this relationship, and implications for treatment.
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Seligman et al. (2015) studied this question.
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