January 1, 1995Health Psychology
Major depression and medication adherence in elderly patients with coronary artery disease.
Why the study?
Does major depression reduce medication adherence in elderly patients with coronary artery disease?
Structured PICO
Does major depression reduce medication adherence in elderly patients with coronary artery disease?
P
Population
n=55 patients over the age of 64 with coronary artery disease. 10 patients met criteria for major depression.
I
Intervention
Major depression (observational exposure)
C
Comparator
No major depression
O
Outcome
Medication adherence to a twice-per-day regimen of low dose aspirin, assessed by an unobtrusive electronic monitoring device
Major depression is associated with significantly poorer adherence to prophylactic aspirin in elderly patients with coronary artery disease.
Authors
Discussion
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Implication
Depression associated with poorer aspirin adherence in elderly CAD; leaves open whether screening or treatment improves outcomes.
Cite This Study
Carney et al. (1995) studied this question.