Key result
Diffusion-weighted imaging aids early diagnosis of acute disseminating encephalomyelitis by detecting restricted signal patterns.
Why the study?
Early diagnosis of acute disseminating encephalomyelitis is highly desirable to initiate steroid therapy, and the study aimed to show the potential diagnostic value of diffusion-weighted imaging.
Does diffusion-weighted imaging (DWI) improve the detection of acute demyelinating lesions in acute disseminating encephalomyelitis (ADEM)?
Case Report (n=1)
No
Does diffusion-weighted imaging (DWI) improve the detection of acute demyelinating lesions in acute disseminating encephalomyelitis (ADEM)?
DWI can be a valuable adjunct to conventional MRI in diagnosing acute disseminating encephalomyelitis by detecting acute demyelinating lesions.
Advanced MRI may aid timely ADEM diagnosis for prompt steroids; leaves open incremental value pending prospective validation.
Acute disseminating encephalomyelitis (ADEM) is a treatable inflammatory, demyelinating disorder of the central nervous system. Early application of steroids has been shown to reduce morbidity, therefore, early diagnosis is highly desirable. Magnetic resonance imaging (MRI) is the imaging modality of choice for establishing the diagnosis along with the clinical presentation. The aim of this report is to show the potential diagnostic value of advanced MR techniques such as diffusion-weighted imaging (DWI), which has been found to add to the diagnostic power of MRI in the setting of demyelinating disorder, even in the absence of contrast enhancement. We report a case of ADEM in an 11-year-old boy revealing high signal intensity changes on DWI indicating elevated diffusion.
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Al-Mestady et al. (2008) conducted a case report in Acute disseminating encephalomyelitis (ADEM) (n=1). Diffusion-weighted imaging (DWI) was evaluated on Detection of acute demyelinating lesions. Diffusion-weighted imaging demonstrated a restricted pattern with intense high signal intensity in an 11-year-old boy with acute disseminating encephalomyelitis, aiding in early diagnosis.
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