What does this research mean for the field?

Kenyan blood donors exhibit significant RhD/RHD phenotype/genotype discrepancies and RH allele diversity, demonstrating that genotyping can improve RH typing accuracy and reduce the risk of patient alloimmunization. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to investigate genetic diversity in RHD and RHCE genes among Kenyan blood donors.

April 24, 2026Transfusion0 citationsOpen Access

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Genetic diversity in RHD and RHCE genes among a selected Kenyan blood donor population

SSSandra A. Sowah APAlexis J. Perros RGRachel GithiomiKenya National Blood Transfusion Services

Key Points

This research aims to investigate genetic diversity in RHD and RHCE genes among Kenyan blood donors.
Conducted genotyping to determine RHD and RHCE phenotypes and genotypes.
Analyzed discrepancies in RhD/RHD and allele diversity among donors.
Identified RH allele diversity affecting antigen expression.
Revealed discrepancies in RhD/RHD phenotyping that may risk alloimmunization.

Abstract

Genotyping revealed RhD/RHD phenotype/genotype discrepancies and RH allele diversity among Kenyan donors, including RHCE variants affecting high- and low-prevalence antigen expression. These findings highlight the role of genotyping to improve accuracy for RH typing to minimize the risk of patient alloimmunization.

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Cite This Study

Sowah et al. (Wed,) studied this question.

synapsesocial.com/papers/69eb0961553a5433e34b3d38 https://doi.org/https://doi.org/10.1111/trf.70205

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